Institute Hyalual

Redermalization

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REDERMALIZATION

Proven improvement of skin quality by increasing its regenerative potential

Unlike other rejuvenation procedures,  

redermalization works in 3 directions all at once:
1

Help in regulation of
biochemical processes in cells

2

Restoration of
water balance

3

Contributes in active
blocking of free radicals

This triple effect is achieved by using of Double Synergic Effect technology: a synergistic effect resulting from two components in the product - high molecular weight hyaluronic acid and succinic acid (in the form of sodium succinate). This is the main advantage of the Redermalization procedure

DOUBLE SYNERGIC EFFECT TECHNOLOGY

Hyaluronic acid
is a natural material that is contained in neuronal, connective and epithelial tissues
  • Helps to activate anti-inflammatory mediators
  • Restores and maintains water balance
  • Contributes to the synthesis of basic structural proteins
  • Provides mechanical support for tissues
Preparations based on high molecular weight hyaluronic acid are used for the Redermalization.
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Succinic acid
(succinate) is a natural component, which is found in all cells in the body
  • Нelps to normalize microcirculation, contributes to lymphatic drainage
  • Helps to regulate cellular energy exchange
  • Has antioxidant properties
  • Helps to prevent damage of the cell membrane
  • Contributes to the synthesis of basic structural proteins
Succinic acid has been found an important component which has provided a breakthrough in improving skin quality.
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Biorevitalization agent
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Hyaluronic acid
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Redermalization
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High molecular weight hyaluronic acid + succinic acid
More information
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  • Quality confirmed by CE-mark
  • Manufactured according to GMP
  • Improved HA purification technology (Hyalual Purification Technology)
  • Double Synergic Effect technology. Maximum synergistic effect of two components
  • Monodispersity of HA molecules (2.5 million Da)
  • Enhanced buffer protection of redermalization agent
REDERMALIZATION with HYALUAL
and XELA REDERM
PRODUCTS
PROCEDURE PROTOCOL
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REDERMALIZATION
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HYALUAL 1,1%HYALUAL Light / XELA Rederm 1,1%
HYALUAL 1,8%HYALUAL Smart / XELA Rederm 1,8%
HYALUAL 2,2%HYALUAL Booster / XELA Rederm 2,2%

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POST-TREATMENT CARE
IN THE OFFICE
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PROFI DELUX

Aftercare spray
Apply three layers
50 ml

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SAFE SUN

Daily photoaging protection,
SPF 50

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PRESCRIPTION OF POST-
TREATMENT CARE AT
HOME
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PROFI DELUX

Aftercare spray
Apply three layers every three
hours for three days
50 ml

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SAFE SUN

Daily photoaging protection,
SPF 50
Apply once in morning for five
to seven days
150 ml

APPLICATION Regermanization HYALUAL
and XELA REDERM
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Hyalual Light / Xela Rederm 1.1% Hyalual 1.1%
  • Initial procedure for acne, post acne and edematous component (tired, deformative, muscular morphotypes).
  • Fatty, porous skin.
  • Cicatricial changes of any etiology.
  • Can be combined with neurotoxin, thread lifting and/or fillers.
  • Preparation for traumatic procedures.
  • Reduces edematous component and promotes lymphatic drainage..
  • Improves microcirculation.
  • Detoxifies tissue.
  • Lightens skin by 1-2 shades.
  • Brightens under eye circles.
  • Eliminates signs of fatigue.
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Hyalual Smart / Xela Rederm 1.8% Hyalual 1.8%
  • Initial procedure for wrinkling morphotype.
  • Second procedure in protocol for correcting tired, deformative and muscular morphotypes of aging.
  • Dry, dehydrated skin.
  • Bio-reinforcement.
  • Correction of photoaging, photo damage and dyschromia.
  • Preparation for traumatic procedures.
  • Restores dermal water balance..
  • Firms by restoring dermal collagen structure.
  • Reduces pigmentation and lightens skin.
  • Flattens skin's microrelief.
  • Promotes skin radiance.
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Hyalual Booster / Xela Rederm 2.2% Hyalual 2.2%
  • Third and fourth procedure in protocol for Redermalization.
  • Bio-reinforcement and proprietary techniques.
  • Reinforcing with cannula (wrinkling morphotype).
  • Cutaneous depressions.
  • Preparation for traumatic procedures.
  • Helps lift tip of needle.
  • Improves quality of skin by adding firmness.
  • Restores vermilion color.
  • Balances dermal water balance.
Kolgunenko I.I. Fundamentals of Gerontocosmetology. Moscow: Medicine; 1974. 224 p.
REDERMALIZATION FOR MORPHOTYPES
Procedure I
2 weeks
Procedure II
2 weeks
Procedure III
TIRED FACE HYALUAL Light / XELA REDERM 1,1% HYALUAL 1,1% Lymphatic drainage, papular
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HYALUAL Light / XELA REDERM 1,1% или HYALUAL 1,1% или
HYALUAL Smart / XELA REDERM 1,8% HYALUAL 1,8% Papular
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HYALUAL Booster / XELA REDERM 2,2% HYALUAL 2,2% Linear
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DEFORMATIVE HYALUAL Light / XELA REDERM 1,1% HYALUAL 1,1% Lymphatic drainage, papular
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HYALUAL Light / XELA REDERM 1,1% HYALUAL 1,1% Lymphatic drainage, papular
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HYALUAL Smart / XELA REDERM 1,8% или HYALUAL 1,8% или
HYALUAL Booster / XELA REDERM 2,2% HYALUAL 2,2% Linear
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WRINKLING HYALUAL Smart / XELA REDERM 1,8% HYALUAL 1,8% Papular, linear
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HYALUAL Smart / XELA REDERM 1,8% или HYALUAL 1,8% или
HYALUAL Booster / XELA REDERM 2,2% HYALUAL 2,2% Papular, linear
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HYALUAL Smart / XELA REDERM 1,8% или HYALUAL 1,8% или
HYALUAL Booster / XELA REDERM 2,2% HYALUAL 2,2% Linear
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MUSCULAR morphotype HYALUAL Light / XELA REDERM 1,1% HYALUAL 1,1% Lymphatic drainage, papular
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HYALUAL Smart / XELA REDERM 1,8% HYALUAL 1,8% Papular, linear
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HYALUAL Booster / XELA REDERM 2,2% HYALUAL 2,2% Linear
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Kolgunenko I.I. Fundamentals of Gerontocosmetology. Moscow: Medicine; 1974. 224 p.
Designation:
img - Needle
img - Cannula
PROCEDURE PROTOCOL
STEP №1
Correctly determine the type of aging skin by Kolgunenko
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MORPHOTYPE TIRED FACE WRINKLING DEFORMATIVE MUSCULAR
Outward appearance/symptoms

The face looks refreshed upon waking, but by night the skin becomes drawn and tired looking with a “sad” appearance.

Dark bags under the eyes, deepening of lacrimonasal and nasolabial folds, and drooping at the corners of the mouth are visible. The complexion appears gray and dull with an uneven skin tone and areas of hyperpigmentation.

Facial contours appear to lose volume.

The muscular framework of the face and subcutaneous fat are weakly expressed. Facial skin hydration decreases, leaving the complexion with a “dried out” look. A network of fine wrinkles form, giving the skin a crepey appearance. This is made worse by a dehydrated, uneven complexion. The main areas of concern are the crow's feet around the outer eye corners, horizontal wrinkles on the forehead, deep nasolabial folds, and vertical lines near the lip.

The face looks tired and drained due to soft tissue laxity. Bags under the eyes are typical, as are drooping upper lids, buccula (double chin), sagging jowls, deflated cheeks, sharp nasolabial furrows, and thickening of the nose’s alar.

It is often accompanied by reddening of the cheeks due to rosacea and/or hyperpigmentation.

Deep, static forehead wrinkles, vertical furrows between the brows, pronounced nasolabial folds, alar thickening, and gaunt cheekbones are all typical. The face does not droop downward, and subcutaneous fat is almost absent. Uneven pigmentation and dryness are often present.

Facial structure remains almost unchanged.

Leading pathogenesis mechanisms

Age-related lymphatic changes, along with a decrease in circulation, low muscle tone, and skin elasticity are known causes.

Leading causes include skin dehydration, the destruction of the collagen framework within the dermis, and low muscle tone in the face.

The weakened soft tissues droop, pulling the skin downward along with it. The muscle frame ceases to support subcutaneous tissue. A large amount of subcutaneous fat retains fluid and contributes to the development of edema (swelling). A reduction in the quantity and quality of collagen and elastin fibers means there is no longer a framework to support the skin.

The facial musculature appears prominent since the skin lacks adequate volume from subcutaneous fatty tissue. Due to the active clonus of the facial muscles and loss of fat pads under the skin, deep creases and folds begin to form.

Focus of therapy

The goal of treatment is to reduce the appearance of superficial epidermal wrinkles by boosting microcirculation, lightening the skin, and improving the tone of facial muscles.

Treatment focuses on restoring skin’s water balance and strengthening facial muscles to improve skin quality.

Therapy aims to promote microcirculation and lymphatic drainage to reduce edema, and to stimulate collagen and elastin production.

The goal is to encourage microcirculation and increase hyaluronic acid levels to restore volume where fat pads in the face once were.

Kolgunenko I.I. Fundamentals of Gerontocosmetology. Moscow: Medicine; 1974. 224 p.
STEP №2
To prepare skin for the procedure
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PRODUCT APPLICATION TECHNIQUE ACTION
Anesthetic

Cover the product on various parts of the skin surface, then gradually spread it over the entire area that was treated for redermalization.

Anesthetizes skin in preparation for treatment.

Profi Delux

Five minutes later, apply Profi Delux spray at a distance of 25-30 cm from the skin surface for a duration of three seconds. Shake well before using.

Apply three layers.

Replaces the need for occlusal film.

Speeds the anesthetic’s onset of action.

STEP №3
Administer the recommended course of redermalization
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TIRED FACE

Recommended quantity and frequency of procedures

3 procedures at a frequency of once every 2 weeks.

Procedure 1:

Product

Administration technique

Hyalual Light / Xela Rederm 1.1% - 2 ml.

Papular.

Goal of procedure

Improve microcirculation, correct hyperpigmentation, and prevent the appearance of epidermal wrinkles.

Immediate results

Refreshed complexion and smoothed facial contours.

Postponed results

During the next month after treatment, dark circles and bags under the eyes become less visible, the complexion is restoring, and signs of fatigue and “sadness” reduce.

Procedure 2:

Product

Administration technique

Hyalual Light / Xela Rederm 1.1% - 2 ml.

Papular.

Goal of procedure

Increase turgor (elasticity), flatten the skin’s microrelief, and correct pigmentation.

Immediate results

Revived complexion and preservation of facial contours.

Postponed results

Skin elasticity increases and lacrimonasal and nasolabial furrows appear smoother.

Procedure 3:

Product

Administration technique

Hyalual Booster / Xela Rederm 2.2% - 2 ml.

Linear, cannula.

Goal of procedure

Reduce lacrimonasal and nasolabial furrows and improve skin texture.

Immediate results

Reduction of lacrimonasal and nasolabial folds, along with improved contours of the middle and lower third of the face.

Postponed results

Qualitative improvement in skin texture and color.

WRINKLING

Recommended quantity and frequency of procedures

2-3 procedures at a frequency of once every 2 weeks.

Procedure 1:

Product

Administration technique

Hyalual Smart / Xela Rederm 1.8% - 2 ml.

Papular, linear.

Goal of procedure

Restore water balance in the dermis and initiate full-fledged collagen and elastin synthesis.

The linear technique is the first stage of correction for dermal wrinkles.

Immediate results

Restoration of skin nutrition, improved radiance, and a reduced quantity of superficial wrinkles..

Postponed onset

Following the next week skin is more moisturized, dryness is reduce and the depth and number of dermal wrinkles are reduced.

Procedure 2:

Product

Administration technique

Hyalual Smart / Xela Rederm 1.8% - 2 ml.

Papular.

Hyalual Booster / Xela Rederm 2.2% - 2 ml.

Linear.

Goal of procedure

Enhance skin’s glow.

The linear technique is the second stage for correcting dermal wrinkles.

Immediate results

Glowing complexion and reduction of superficial wrinkles.

Postponed onset

Skin radiance improves and wrinkles reduce.

Procedure 3:

Product

Administration technique

Hyalual Smart / Xela Rederm 1.8% - 2 ml.

Linear.

Hyalual Booster / Xela Rederm 2.2% - 2 ml.

Cannula.

Goal of procedure

Restore intermuscular volume and promote dermal growth.

Immediate results

Deep hydration of the dermis, and lifting of the middle and lower third of the face.

Postponed onset

Full restoration of the skin’s dermal layer and reduced hyperpigmentation.

DEFORMATIVE

Recommended quantity and frequency of procedures

3 procedures: Initial treatment, the second 2 weeks later, the third 3 weeks later.

Procedure 1:

Product

Administration technique

Hyalual Light / Xela Rederm 1.1% - 2 ml.

Papular (lymph drainage).

Goal of procedure

Improve microcirculation and lymphatic drainage, reduce edema, and stimulate collagen and elastin production.

Immediate results

Reduction of puffiness and dullness improved skin tone.

Postponed onset

Soft tissue swelling is reduced with improved angiogenesis. Enhanced microcirculation and lymphatic drainage are present.

Procedure 2:

Product

Administration technique

Hyalual Light / Xela Rederm 1.1% - 2 ml.

Papular.

Goal of procedure

Normalize lymph efflux and encourage microcirculation.

Immediate results

Reduction of puffiness, an evened skin tone, and elimination of skin dullness.

Postponed onset

The swelling in deeper soft tissues is reducing with improved angiogenesis, along with enhanced microcirculation and lymphatic drainage.

Procedure 3:

Product

Administration technique

Hyalual Smart / Xela Rederm 1.8% - 2 ml.

Papular.

Hyalual Booster / Xela Rederm 2.2% - 2 ml.

Linear, along the vector lines.

(aproprietary technique of lifting)

Goal of procedure

Qualitative improvement of the skin structure due to the thickening of dermal fibers.

The proprietary linear application technique reduces skin folds, resulting in a visible lifting effect due to normalized collagen and elastin production.

Immediate results

Lifting at the “needle tip”.

Postponed onset

On the 21-28th day, significant lifting develops due to increased collagen and elastin production within fibroblasts.

Qualitative improvement in skin texture results due to thickening of fibrous structure in the skin’s dermal layer. The lifting effect lasts 5-8 months.

MUSCULAR

MORPHOTYPE

MUSCULAR

Recommended quantity and frequency of procedures

2-3 procedures at a frequency of once every 2 weeks.

Procedure 1:

Product

Administration technique

Hyalual Light / Xela Rederm 1.1% - 2 ml.

Papular.

Goal of procedure

Kickstart the recovery mechanism of the dermis and normalize metabolism in fibroblasts.

Immediate results

Glowing skin and reduction of superficial wrinkles and fine lines.

Postponed onset

The skin is more moisturized, hyperpigmentation decreases, and skin elasticity increases.

Procedure 2:

Product

Administration technique

Hyalual Smart / Xela Rederm 1.8% - 2 ml.

Papular, cannulation.

Goal of procedure

Promotion of dermal growth.

Immediate results

Glowing skin and a reduction in superficial wrinkles.

Postponed onset

Reduction of overly-prominent facial muscle contours and reduced evidence of skin hyperpigmentation. The moisture balance within skin tissue improves, and fine wrinkles are reduced.

Procedure 3:

Product

Administration technique

Hyalual Booster / Xela Rederm 2,2% - 2 ml.

Linear, cannula.

Goal of procedure

Reduce skin creases and provide a significant lifting effect by normalizing collagen and elastin production.

Immediate results

Lifting at the “needle tip”.

Postponed onset

Reduction of ptosis (drooping) and a decrease in the depth of nasolabial folds.

Skin tone lightens and wrinkles are eliminated.

Dermal creases appear significantly smoothed.

Kolgunenko I.I. Fundamentals of Gerontocosmetology. Moscow: Medicine; 1974. 224 p.
STEP №4
Post injection care
Turn
PRODUCT APPLICATION TECHNIQUE ACTION

Profi Delux

Post-procedure spray

After the procedure is complete, spray at a distance of 25-30 cm away from the skin surface for three seconds. Shake well beforehand. Apply in three layers.

Advise patient that the mild side effects of the spray (redness, skin irritation, dryness, and burning) are temporary.

Reduces recovery time.

Allows the patient to quickly see the result of the procedure.

Delivers a pleasant feeling of freshness on the patient’s skin after treatment.

Safe Sun SPF 30, 50

Photo-ageing protection

Dot the product on various parts of the skin surface, then gradually spread it over the entire area that was treated for redermalization.

Derma-protector RE-DERM offers maximum skin protection against sun damage. Exceptional UVA and UVB protection guards against hyperpigmentation, making it especially useful for damaged skin.

Preserves the integrity, structure, and function of the dermis.

Performs double duty as a daily moisturizer.

Profi Delux

Post-procedure spray

Five minutes after sunblock application, spray Profi Delux at a distance of 25-30 cm from the skin surface for three seconds, shaking well first.

Improves the onset of action for the cream.

STEP №5
Prescription of home post-injection care
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PRODUCT APPLICATION TECHNIQUE ACTION

Profi Delux 50 ml

Post-procedure spray

Apply three layers every three hours.

Atomize spray at a distance of 25-30 cm from the skin surface for three seconds, shaking well first.

Reduces recovery time.

Allows the patient to quickly see the result of the procedure.

Delivers a pleasant feeling of freshness on the patient’s skin after treatment.

Safe Sun SPF 30, 50

Photo-ageing protector

Each morning, apply Safe Sun SPF 30 or 50 for protection against UVA and UVB rays.

.

Derma-protector RE-DERM offers maximum skin protection against sun damage. Exceptional UVA and UVB protection guards against hyperpigmentation, making it especially useful for damaged skin.

Preserves the integrity, structure, and function of the dermis.

Performs double duty as a daily moisturizer.

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